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Cover of StepLobe Mnemonics for USMLE Step 1, 2nd edition: a glowing brain among glass cubes, with 717 mnemonics, 161 real photos, 169 diagrams and 136 questions.

New 2nd edition · instant access

Every Step 1 list, back when you need it.

StepLobe Mnemonics for USMLE® Step 1. 717 mnemonics with what every letter means, why it's true and the exact way the exam will describe the patient.

  • Every letter explained, plus the mechanism, so you can rebuild a list you half-forget
  • An exam hook on every card: what the stem shows, and what to think
  • 161 real clinical photos and 169 original diagrams, not cartoons
  • 136 exam-style questions and a rapid-recall sheet in every section
$29$49Save $20 · launch price until 30 Nov 2026
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From the team behind the StepLobe Main Book, reviewed by 28 physicians led by Prof. Malihe Amirian, MD.

717
mnemonics
161
real clinical photos
169
original diagrams
136
exam-style questions
582
full-color pages
17
subjects, Step 1 order

How every card works

Not just a list of letters. A card that teaches.

A mnemonic only helps if you know what each letter means and why it's true. That's why all 717 cards follow the same five-part pattern.

A real card from the book: PROVe for tetralogy of Fallot, with each letter explained, why it works, a boot-shaped heart X-ray and the exam hook.
A real card from the Cardiovascular section (page 13).
  1. 1

    The mnemonic

    Short and vivid: a classic you may know, or a new StepLobe one built to stick.

  2. 2

    Every letter, decoded

    What each letter stands for, with the one detail the exam wants beside it.

  3. 3

    Why it works

    The mechanism in two lines, so a forgotten letter can be rebuilt instead of guessed.

  4. 4

    The real picture

    A licensed clinical photo or an original diagram whenever seeing it is what makes it stick.

  5. 5

    The exam hook

    How an NBME-style stem describes the patient, and what you should think.

Look inside

Flip through real pages.

Twelve pages from across the book, exactly as they print. Want more? The free sample has 26 pages, including the whole first Cardiovascular chapter and its questions.

Sample page 9: Cardiovascular · Murmurs, with a one-cycle diagram and a 'tell them apart' table

Page 9 · 1 of 12

Cardiovascular · Murmurs, with a one-cycle diagram and a 'tell them apart' table

Read all 26 free pages (PDF)

No sign-up. The sample opens in a new tab.

New in the 2nd edition

Rebuilt from the first page to the last.

Same promise, much better book: clearer cards, real images and questions to prove you know it.

Rewritten card by card

Each of the 717 cards was checked against current guidelines and nomenclature, and rewritten to teach the mechanism, not just the list.

Real photos replace drawings

161 licensed clinical photographs (rashes, smears, X-rays, CT, histology) and 169 new diagrams drawn for this edition.

Original mnemonics

113 mnemonics borrowed from commercial review books were replaced with new StepLobe ones, and weak ones were made shorter and catchier.

Test yourself

136 exam-style questions with full explanations, plus a rapid-recall sheet at the end of every section.

What's inside

All 17 subjects, in Step 1 order.

Each section opens with a roadmap and closes with 8 exam-style questions and a rapid-recall sheet. Classics like PROVe and FROM JANE sit beside new StepLobe mnemonics.

  • Cardiovascular

    46 cards

    Murmurs, congenital heart disease, endocarditis, pericardium, arrhythmias, heart failure, vasculitis and cardiac drugs

    PROVeFROM JANEHACEK
  • Renal & Acid–Base

    32 cards

    Acid–base, glomerular disease, diuretics, electrolytes and stones

    GOLDMARKCLEVER PD
  • Pulmonary

    32 cards

    Lung anatomy, obstructive and restrictive disease, pneumonia, embolism and lung cancer

    RALSCLUBBINGSPHERE
  • Neurology & Cranial Nerves

    85 cards

    Cranial nerves, brainstem and stroke syndromes, spinal cord, seizures, dementia and neuro drugs

    LR6 SO4 R3O TOM CATPICA
  • Gastrointestinal

    56 cards

    Embryology, GI bleeding, liver and biliary disease, pancreas, bowel disease and GI drugs

    SAD PUCKERNAVELRIP
  • Hematology & Oncology

    47 cards

    Anemias, coagulation, leukemias and lymphomas, tumor markers and chemotherapy

    TAILSLEADPCT
  • Endocrine

    40 cards

    Pituitary, thyroid, adrenal, calcium, diabetes and MEN syndromes

    FLAT PiGLMNOPBIG HANDS
  • Reproductive

    26 cards

    Embryology, pregnancy, ovarian and testicular disease, sex chromosome disorders and breast

    VEAL CHOPAPGARHELLP
  • Musculoskeletal & Anatomy

    48 cards

    Brachial plexus, nerves and muscles, joints, bone disease and rheumatology

    SITSERBSSALT
  • Dermatology

    21 cards

    Skin layers, blistering disease, skin cancer and the classic rashes

    PSORIASISNASANODOSUM
  • Psychiatry

    38 cards

    Mood, psychosis, anxiety, personality, substance use and psychiatric drugs

    SIG E CAPSDABDASASH
  • Microbiology

    60 cards

    Bacteria, viruses, fungi, parasites and antimicrobials

    SHaKE the SPoNGePHAGEFRIDGE
  • Immunology

    25 cards

    Cells and cytokines, hypersensitivity, immunodeficiency and transplant

    GAMEDACIDBIG HARM
  • Pharmacology

    50 cards

    Pharmacokinetics, autonomic drugs, toxicology, antidotes and drug side effects

    DUMBBELSSRACE By GPSPEA
  • Biochemistry & Nutrition

    56 cards

    Metabolism, enzymes, storage diseases, vitamins and minerals

    GARLICMILDABCD
  • Genetics

    29 cards

    Inheritance patterns, trisomies, trinucleotide repeats and genetic syndromes

    CLAMPSDown’s ABCDEFRIEDreich
  • Biostatistics & Ethics

    26 cards

    Study design, test statistics, bias, ethics and patient safety

    PARQWIPECURVES

Why it sticks

A mnemonic you understand is one you keep.

FeatureStepLobe MnemonicsTypical mnemonic lists
What every letter meanssometimes
Why it's true (the mechanism)rarely
How the exam describes it
Real photos and diagrams
Exam-style questions to test yourself
Checked against current guidelinesoften outdated
Organized by subject, with A–Z indexesscattered
Dr. Aryan, founder of StepLobe

“Struggling doesn't mean you're failing. It means you're learning something hard.”

I built StepLobe to be the study partner I wished I'd had. Every mnemonic in this book comes with the reason it is true, so you can walk into the exam room calm, ready and proud of what you've built.

Dr. Aryan · Founder of StepLobe

StepLobe Mnemonics, 2nd edition cover

Start remembering today.

  • 717 mnemonics, every letter explained
  • 161 real photos · 169 diagrams
  • 136 exam-style questions
  • Rapid-recall sheets and A–Z indexes
Get instant access · $29

$49 · launch price until 30 Nov 2026

Want everything? The Complete Step 1 Vault includes this book, both Main Book volumes, all 17 Systems books and 12 months of Pro for $249.

Questions about the book

How do I get the book after I pay?+

Right away. Your personal copy is ready on the thank-you page, in My books in your StepLobe account, and in an email. Sign in with the email you used at checkout.

Can I read it on my phone or iPad?+

Yes. It's a full-color 8.5 × 11 book that reads best on a tablet or computer and works on a phone too.

What's new in the 2nd edition?+

Everything was rebuilt: 717 rewritten cards, 161 real photos, 169 new diagrams, 136 exam-style questions, and 113 borrowed mnemonics replaced with original ones.

Who made it?+

Dr. Aryan and the StepLobe team. From the team behind the StepLobe Main Book, reviewed by 28 physicians led by Prof. Malihe Amirian, MD.

Is there a print edition?+

Yes. The full-color paperback is coming to Amazon soon. The digital edition here is the same book, available today for less.

Does the book include the question banks?+

No. The banks, flashcards and study plan are in StepLobe Pro. The Complete Step 1 Vault ($249) includes this book, every other StepLobe book and 12 months of Pro.

Is this an official USMLE or NBME book?+

No. StepLobe is not affiliated with or endorsed by the FSMB, the NBME or the USMLE program. It's original study material, not medical advice.

USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). StepLobe is not affiliated with or endorsed by the FSMB, the NBME or the USMLE program. For study only. Not medical advice. © Opaline Clinique Limited. Launch price until 30 Nov 2026.